Findings do not support Corticosteroid injections for Knee Osteoarthritis.
A Randomised Clinical Trial.
Research Question: What are the effects of intra-articular injection of 40 mg of triamcinolone acetonide every 3 months on a progression of cartilage loss and knee pain in patients with osteoarthritis?
They found: “In a randomized clinical trial of 140 patients with symptomatic knee osteoarthritis, the use of intra-articular triamcinolone compared with intra-articular saline resulted in greater cartilage volume loss. There was no significant difference in knee pain severity between treatment groups".
They have concluded: “Among patients with symptomatic knee osteoarthritis, 2 years of intra-articular triamcinolone, compared with intra-articular saline, resulted in significantly greater cartilage volume loss and no significant difference in knee pain. These findings do not support corticosteroids injection for patients with symptomatic knee osteoarthritis".
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